Symbol Name ID |
Yap1
yes-associated protein 1 MGI:103262 |
Darker colors indicate more annotations |
Human Phenotypes | Hematuria |
Disease(s) Associated with YAP1 | |
uveal coloboma-cleft lip and palate-intellectual disability |
Mouse Phenotypes | abnormal kidney cortex morphology |
podocyte foot process effacement |
abnormal renal glomerulus morphology |
decreased renal glomerulus number |
abnormal kidney development |
abnormal metanephros morphology |
abnormal nephrogenic zone morphology |
abnormal kidney medulla morphology |
abnormal kidney papilla morphology |
renal hypoplasia |
abnormal renal tubule morphology |
abnormal loop of Henle morphology |
abnormal proximal convoluted tubule morphology |
decreased renal tubule number |
impaired branching involved in ureteric bud morphogenesis |
anuria |
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Availability | Mouse Genotype | ||||||||||||||||
Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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